aching heart, agony, agony of mind, anguish, bale, bitterness, bleeding heart, brokenheartedness, crushing, depression, depth of misery, desolation, despair, extremity, grief, heartache, heartbreak, heartbrokenness, heartsickness, heartsoreness, heavy heart, infelicity, melancholia, melancholy, misery, prostration, sadness, suicidal despair, woe, wretchedness