abate, afflict, attenuate, beat, blunt, break, burn out, castrate, cramp, cripple, damp, dampen, deaden, debilitate, defeat, demasculinize, dematerialize, derange, desex, desexualize, devitalize, disable, disembody, disorder, do in, do up, drain, dull, effeminize, emasculate, enfeeble, etherealize, etiolate, eviscerate, exhaust, extenuate, fag, fag out, fatigue, flag, frazzle, gruel, harass, hospitalize, incapacitate, indispose, invalid, jade, knock out, knock up, lay low, lay up, mitigate, overfatigue, overstrain, overtire, overweary, poop, poop out, prostrate, rarefy, rattle, reduce, sap, shake, shake up, sicken, soften up, spiritualize, sterilize, strain, subtilize, tire, tire out, tire to death, tucker, unbrace, undermine, unman, unnerve, unstrengthen, unstring, use up, weaken, wear, wear down, wear on, wear out, weary, wilt, wind