| Ossify 1. (v. t.) To harden into bone; to change from a soft substance into bone, as by the deposition of lime salts. 2. (v. t.) Fig.: To harden; as, to ossify the heart. 3. (v. i.) To become bone; to change from a soft tissue to a hard bony tissue. Thesaurus Entries anneal, brutalize, calcify, callous, case harden, cornify, firm, fossilize, harden, indurate, inure, lapidify, lithify, petrify, steel, temper, toughen, vitrify | ![]() |