Pestilence

1. (n.) A raging epidemic; specifically, the bubonic plague; hence, any contagious or infectious epidemic disease that is virulent and devastating.

2. (n.) Fig.: That which is pestilent, noxious, or pernicious to the moral character of great numbers.

Thesaurus Entries

Black Death, affliction, ambulatory plague, bane, black death, black plague, blight, bubonic plague, bugbear, burden, calamity, cancer, canker, cellulocutaneous plague, crushing burden, curse, death, defervescing plague, destruction, disease, epidemic, epiphytotic, epizootic, evil, glandular plague, grievance, harm, hemorrhagic plague, infliction, larval plague, murrain, nemesis, open wound, pandemia, pandemic, pest, pesthole, plague, plague spot, pneumonic plague, premonitory plague, running sore, scourge, septicemic plague, siderating plague, thorn, torment, tuberculosis, vexation, visitation, white plague, woe